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ANAEMIA

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ANAEMIA

 

 

CHAPTER ONE

 

1.0     Introduction

 

1.1     Anaemia

 

1.1.1  Biochemistry

 

1.2     Iron therapy

 

1.3     Biosynthesis of Heme

 

CHAPTER TWO

 

2.0     Classification

 

2.1     Hyporegenerative

 

2.1.1  Aplastic

 

2.1.2  Pure red cell aplasia (PRCA)

 

2.1.3 related to the myelodysplastic syndrome

 

2.1.4  Deficiency

 

2.1.5  Bone marrow infiltration and fibrosis

 

2.1.6  chronic disease (ACD)

 

2.1.7  chronic renal failure

 

2.2     Regenerative

 

2.2.1  Immune haemolytic

 

2.2.2  Sickle cell

 

2.2.3  due to enzymopathies and red cell membrane defects

 

2.2.4  Haemorrhagic

 

CHAPTER THREE

 

3.0     Selected

 

3.1     Pure red cell aplasia

 

3.2     B12 deficiency

 

3.3     Immune haemolytic

 

3.3.1  Classification

 

3.3.2  Pathophysiology of immune haemolytic

 

3.3.3  Diagnosis of haemolytic

 

3.4     Non-immune haemolytic

 

3.4.1  Paroxysmal nocturnal haemoglobinuria (PNH)

 

3.4.2  Microangiopathic disorders

 

3.4.3  Haemolysis secondary to toxic agents and other causes

 

CHAPTER FOUR

 

4.0     Conclusion

 

References

 

 

 

 

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